2025 Fantasy Football: Running Backs Thriving Behind Elite Offensive Lines

The ability to open up running lanes is as crucial for offensive lines as finding those lanes is for the backs they lead. In the 2025 season, fantasy football enthusiasts are keeping a keen eye on several offenses with promising blocking capabilities. Here’s a breakdown of the lines setting their runners up for success.

Indianapolis Colts

The Colts’ offensive line, despite some personnel changes, continues to impress with their run-blocking prowess. They are adept at paving the way, evidenced by last season's 2.34 yards before contact per rush. Jonathan Taylor stands to benefit as the primary rusher, especially given his heavy utilization in red zone situations.

Should Taylor face any setbacks, rookie DJ Giddens could emerge as a valuable fantasy asset, relying on the Colts' sustained line integrity. With the addition of Jalen Travis from Iowa State, the Colts aim to maintain their dynamic ground game.

Arizona Cardinals

Arizona sits comfortably atop league standings in creating yards before contact, setting up James Conner for a potential breakout year. The Cardinals have perfected a balanced attack, as seen in their 40 percent rushing stuff rate and solid pass-rushing complement.

In 2025, Conner, alongside emerging talent Trey Benson, could dominate as Arizona eyes positive touchdown regression. With red zone statistic leaders like Conner, the Cardinals’ run-first strategy might just prove conducive to fantasy stardom.

Atlanta Falcons

With a line renowned for its ability to bulldoze defenses, the Falcons lay the foundation for Bijan Robinson’s continued success. Atlanta's league-leading run metrics make them a powerhouse in ground gains, promising significant output from not only Robinson but also backup hope Tyler Allgeier.

If Robinson falters, Allgeier represents a strategic bench spot, capitalizing on the formidable Falcon front.

Tampa Bay Buccaneers

Tampa optimized their ground attack as last season progressed, highlighted by a diverse running strategy and the resilience of their line. The Bucs’ adjusted tactics align with run-first ideologies, turning to talented back Bucky Irving when needed.

In the event of injury, prizing Rachaad White later in drafts could pay dividends, thanks to his catching skills and potential to exploit Tampa's blocking. While not as efficient on the ground historically, White’s prospects might soar behind top-tier protection.